Ontology highlight
ABSTRACT:
SUBMITTER: Mast FD
PROVIDER: S-EPMC8043454 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Mast Fred D FD Fridy Peter C PC Ketaren Natalia E NE Wang Junjie J Jacobs Erica Y EY Olivier Jean Paul JP Sanyal Tanmoy T Molloy Kelly R KR Schmidt Fabian F Rutkowska Magda M Weisblum Yiska Y Rich Lucille M LM Vanderwall Elizabeth R ER Dambrauskas Nicolas N Vigdorovich Vladimir V Keegan Sarah S Jiler Jacob B JB Stein Milana E ME Olinares Paul Dominic B PDB Hatziioannou Theodora T Sather D Noah DN Debley Jason S JS Fenyö David D Sali Andrej A Bieniasz Paul D PD Aitchison John D JD Chait Brian T BT Rout Michael P MP
bioRxiv : the preprint server for biology 20210410
Despite the great promise of vaccines, the COVID-19 pandemic is ongoing and future serious outbreaks are highly likely, so that multi-pronged containment strategies will be required for many years. Nanobodies are the smallest naturally occurring single domain antigen binding proteins identified to date, possessing numerous properties advantageous to their production and use. We present a large repertoire of high affinity nanobodies against SARS-CoV-2 Spike protein with excellent kinetic and vira ...[more]