Ontology highlight
ABSTRACT:
SUBMITTER: Spolaor S
PROVIDER: S-EPMC8044361 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Spolaor Simone S Scheve Martijn M Firat Murat M Cazzaniga Paolo P Besozzi Daniela D Nobile Marco S MS
Frontiers in genetics 20210331
Combination therapies proved to be a valuable strategy in the fight against cancer, thanks to their increased efficacy in inducing tumor cell death and in reducing tumor growth, metastatic potential, and the risk of developing drug resistance. The identification of effective combinations of drug targets generally relies on costly and time consuming processes based on <i>in vitro</i> experiments. Here, we present a novel computational approach that, by integrating dynamic fuzzy modeling with mult ...[more]