Peripheral blood mononuclear cells (PBMC) microbiome is not affected by colon microbiota in healthy goats.

ABSTRACT:

Background

The knowledge about blood circulating microbiome and its functional relevance in healthy individuals remains limited. An assessment of changes in the circulating microbiome was performed by sequencing peripheral blood mononuclear cells (PBMC) bacterial DNA from goats supplemented or not in early life with rumen liquid transplantation.

Results

Most of the bacterial DNA associated to PBMC was identified predominantly as Proteobacteria (55%) followed by Firmicutes (24%), Bacteroidetes (11%) and Actinobacteria (8%). The predominant genera found in PBMC samples were Pseudomonas, Prevotella, Sphingomonas, Acinetobacter, Corynebacterium and Ruminococcus. Other genera such as Butyrivibrivio, Bifidobacterium, Dorea and Coprococcus were also present in lower proportions. Se

SUBMITTER: Pena-Cearra A 

PROVIDER: S-EPMC8048065 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature