In vivo Calcium Imaging of Mouse Geniculate Ganglion Neuron Responses to Taste Stimuli.

ABSTRACT: Within the last ten years, advances in genetically encoded calcium indicators (GECIs) have promoted a revolution in in vivo functional imaging. Using calcium as a proxy for neuronal activity, these techniques provide a way to monitor the responses of individual cells within large neuronal ensembles to a variety of stimuli in real time. We, and others, have applied these techniques to image the responses of individual geniculate ganglion neurons to taste stimuli applied to the tongues of live anesthetized mice. The geniculate ganglion is comprised of the cell bodies of gustatory neurons innervating the anterior tongue and palate as well as some somatosensory neurons innervating the pinna of the ear. Imaging the taste-evoked responses of individual geniculate ganglion neurons with GCaMP has

SUBMITTER: Fowler BE 

PROVIDER: S-EPMC8048314 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature