Ontology highlight
ABSTRACT:
SUBMITTER: Osana S
PROVIDER: S-EPMC8049066 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Osana Shion S Kitajima Yasuo Y Suzuki Naoki N Nunomiya Aki A Takada Hiroaki H Kubota Takahiro T Murayama Kazutaka K Nagatomi Ryoichi R
Journal of cellular physiology 20201230 7
The ubiquitin-proteasome system is a major protein degradation pathway in the cell. Proteasomes produce several peptides that are rapidly degraded to free amino acids by intracellular aminopeptidases. Our previous studies reported that proteolysis via proteasomes and aminopeptidases is required for myoblast proliferation and differentiation. However, the role of intracellular aminopeptidases in myoblast proliferation and differentiation had not been clarified. In this study, we investigated the ...[more]