Ontology highlight
ABSTRACT:
SUBMITTER: Gong L
PROVIDER: S-EPMC8049234 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Gong Lin L Tang Fei F Liu Ernan E Liu Xiaoli X Xu Huiqiong H Wang Yimei Y Song Yadong Y Liang Jiansheng J
PloS one 20210415 4
A loop-mediated isothermal amplification assay combined with a nanoparticle-based lateral flow biosensor (LAMP-LFB) was established for the rapid and accurate detection of the mobilized colistin resistance gene (mcr-1), which causes the loss of colistin antibacterial efficacy in clinical treatments. The amplification stage of the assay was completed in 60 min at 63°C, and the reaction products could be visually detected by employing the LFB, which provided a fast (within 2 min) and objective met ...[more]