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Triptycene Walled Glycoluril Trimer: Synthesis and Recognition Properties.

ABSTRACT: We report the synthesis of a new acyclic CB[n]-type host (1) that features a central glycoluril trimer capped by triptycene sidewalls. Host 1 has good solubility in water (≈ 3 mM) and does not undergo strong self-association (K_s = 480 M^-1). We probed the geometry of the complexes by analyzing the complexation induced changes in the ¹H NMR spectra and measured the complexation thermodynamics by isothermal titration calorimetry. The conformation of 1 and its packing in the solid state was revealed by single crystal x-ray diffraction measurements.

SUBMITTER: Ndendjio SZ

PROVIDER: S-EPMC8049523 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Triptycene Walled Glycoluril Trimer: Synthesis and Recognition Properties.

Ndendjio Sandra Zebaze SZ Liu Wenjin W Yvanez Nicolas N Meng Zihui Z Zavalij Peter Y PY Isaacs Lyle L

New journal of chemistry = Nouveau journal de chimie 20191128 2

We report the synthesis of a new acyclic CB[n]-type host (1) that features a central glycoluril trimer capped by triptycene sidewalls. Host 1 has good solubility in water (≈ 3 mM) and does not undergo strong self-association (Ks = 480 M-1). We probed the geometry of the complexes by analyzing the complexation induced changes in the 1H NMR spectra and measured the complexation thermodynamics by isothermal titration calorimetry. The conformation of 1 and its packin ...[more]

PMID: 33867799

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