Ontology highlight
ABSTRACT:
SUBMITTER: Zhang W
PROVIDER: S-EPMC8057948 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Zhang Wei W Liu Ting T Li Tianshu T Zhao Xudong X
Cancer gene therapy 20200829 3-4
As important modulators in various physiological processes, circular RNAs (circRNAs) have been increasingly demonstrated in tumors, including papillary thyroid cancer (PTC). Hsa_circRNA_102002 (circ_102002) is a circRNA derived from alternative splicing of ubiquitin-specific peptidase 22 (USP22) transcript, the role of which needs further investigation. Our results suggested the upregulation of circ_102002 in PTC tissues and cells, and its promoting effects on epithelial-mesenchymal transition ( ...[more]