Slow Wave Sleep and EEG Delta Spectral Power are Associated with Cognitive Function in Parkinson's Disease.

ABSTRACT:

Background

Cognitive and sleep dysfunction are common non-motor symptoms in Parkinson's disease (PD).

Objective

Determine the relationship between slow wave sleep (SWS) and cognitive performance in PD.

Methods

Thirty-two PD participants were evaluated with polysomnography and a comprehensive level II neurocognitive battery, as defined by the Movement Disorders Society Task Force for diagnosis of PD-mild cognitive impairment. Raw scores for each test were transformed into z-scores using normative data. Z-scores were averaged to obtain domain scores, and domain scores were averaged to determine the Composite Cognitive Score (CCS), the primary outcome. Participants were grouped by percent of SWS into High SWS and Low SWS groups and compared on CCS and other outcomes usin

SUBMITTER: Wood KH 

PROVIDER: S-EPMC8058231 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature