Prescribing pathways to triple therapy in patients with chronic obstructive pulmonary disease in the United States.

ABSTRACT:

Background

Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines recommend triple therapy (TT) for chronic obstructive pulmonary disease (COPD) patients based on severity. TT utilization by severity is infrequently studied in real-world settings and may deviate significantly from current clinical recommendations. This study describes prescribing pathways to TT among patients with COPD in the United States.

Methods

This study analyzed Geisinger Health System electronic medical records from 1 January 2004 to 30 November 2016. Two retrospective cohorts of COPD patients were included: (1) incident COPD, and (2) incident TT users. COPD treatment patterns, including time to TT, were summarized. Time to TT was estimated using Kaplan-Meier methods. Predictors of t

SUBMITTER: Schabert V 

PROVIDER: S-EPMC8058794 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature