Variable dosage compensation is associated with female consequences of an X-linked, male-beneficial mutation.

ABSTRACT: Recent theory has suggested that dosage compensation mediates sexual antagonism over X-linked genes. This process relies on the assumption that dosage compensation scales phenotypic effects between the sexes, which is largely untested. We evaluated this by quantifying transcriptome variation associated with a recently arisen, male-beneficial, X-linked mutation across tissues of the field cricket Teleogryllus oceanicus, and testing the relationship between the completeness of dosage compensation and female phenotypic effects at the level of gene expression. Dosage compensation in T. oceanicus was variable across tissues but usually incomplete, such that relative expression of X-linked genes was typically greater in females. Supporting the assumption that dosage compensation sc

SUBMITTER: Rayner JG 

PROVIDER: S-EPMC8059673 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature