Ontology highlight
ABSTRACT:
SUBMITTER: Santos IA
PROVIDER: S-EPMC8062466 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Santos Igor Andrade IA Shimizu Jacqueline Farinha JF de Oliveira Débora Moraes DM Martins Daniel Oliveira Silva DOS Cardoso-Sousa Léia L Cintra Adélia Cristina Oliveira ACO Aquino Victor Hugo VH Sampaio Suely Vilela SV Nicolau-Junior Nilson N Sabino-Silva Robinson R Merits Andres A Harris Mark M Jardim Ana Carolina Gomes ACG
Scientific reports 20210422 1
Chikungunya virus (CHIKV) is the etiologic agent of Chikungunya fever, a globally spreading mosquito-borne disease. There is no approved antiviral or vaccine against CHIKV, highlighting an urgent need for novel therapies. In this context, snake venom proteins have demonstrated antiviral activity against several viruses, including arboviruses which are relevant to public health. In particular, the phospholipase A2<sub>CB</sub> (PLA2<sub>CB</sub>), a protein isolated from the venom of Crotalus dur ...[more]