Unknown

Dataset Information

0

An R2R3-MYB Transcription Factor Positively Regulates the Glandular Secretory Trichome Initiation in Artemisia annua L.

ABSTRACT: Artemisia annua L. is known for its specific product "artemisinin" which is an active ingredient for curing malaria. Artemisinin is secreted and accumulated in the glandular secretory trichomes (GSTs) on A. annua leaves. Earlier studies have shown that increasing GST density is effective in increasing artemisinin content. However, the mechanism of GST initiation is not fully understood. To this end, we isolated and characterized an R2R3-MYB gene, AaMYB17, which is expressed specifically in the GSTs of shoot tips. Overexpression of AaMYB17 in A. annua increased GST density and enhanced the artemisinin content, whereas RNA interference of AaMYB17 resulted in the reduction of GST density and artemisinin content. Additionally, neither overexpression lines nor RNAi lines showed an abnormal phenotype in plant growth and the morphology of GSTs. Our study demonstrates that AaMYB17 is a positive regulator of GSTs' initiation, without influencing the trichome morphology.

SUBMITTER: Qin W 

PROVIDER: S-EPMC8063117 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

An R2R3-MYB Transcription Factor Positively Regulates the Glandular Secretory Trichome Initiation in <i>Artemisia annua</i> L.

Qin Wei W   Xie Lihui L   Li Yongpeng Y   Liu Hang H   Fu Xueqing X   Chen Tiantian T   Hassani Danial D   Li Ling L   Sun Xiaofen X   Tang Kexuan K  

Frontiers in plant science 20210409

<i>Artemisia annua</i> L. is known for its specific product "artemisinin" which is an active ingredient for curing malaria. Artemisinin is secreted and accumulated in the glandular secretory trichomes (GSTs) on <i>A. annua</i> leaves. Earlier studies have shown that increasing GST density is effective in increasing artemisinin content. However, the mechanism of GST initiation is not fully understood. To this end, we isolated and characterized an R2R3-MYB gene, <i>AaMYB17</i>, which is expressed  ...[more]

Similar Datasets

Unknown Global characterization of Artemisia annua glandular trichome transcriptome using 454 pyrosequencing.
| S-EPMC2763888 | biostudies-literature
Unknown The Light- and Jasmonic Acid-Induced <i>AaMYB108-like</i> Positive Regulates the Initiation of Glandular Secretory Trichome in <i>Artemisia annua</i> L.
| S-EPMC10455203 | biostudies-literature
Unknown Investigation of glandular trichome proteins in Artemisia annua L. using comparative proteomics.
| S-EPMC3414485 | biostudies-literature
Unknown AaMYC3 bridges the regulation of glandular trichome density and artemisinin biosynthesis in Artemisia annua.
| S-EPMC11772365 | biostudies-literature
Unknown Characterisation of the Mentha canadensis R2R3-MYB transcription factor gene McMIXTA and its involvement in peltate glandular trichome development.
| S-EPMC9047286 | biostudies-literature
Unknown AaMYB15, an R2R3-MYB TF in Artemisia annua, acts as a negative regulator of artemisinin biosynthesis.
| S-EPMC8174473 | biostudies-literature
Unknown AabHLH112, a bHLH transcription factor, positively regulates sesquiterpenes biosynthesis in <i>Artemisia annua</i>.
| S-EPMC9478121 | biostudies-literature
Unknown AaABF3, an Abscisic Acid-Responsive Transcription Factor, Positively Regulates Artemisinin Biosynthesis in Artemisia annua.
| S-EPMC6279931 | biostudies-literature
Unknown Differential transcriptome analysis of glandular and filamentous trichomes in Artemisia annua.
| S-EPMC3878173 | biostudies-literature
Unknown Profiling of phytohormone-specific microRNAs and characterization of the miR160-ARF1 module involved in glandular trichome development and artemisinin biosynthesis in Artemisia annua.
| S-EPMC9946145 | biostudies-literature