Faded Critical Dynamics in Adult Moyamoya Disease Revealed by EEG and fMRI.

ABSTRACT: Criticality is considered a dynamic signature of healthy brain activity that can be measured on the short-term timescale with neural avalanches and long-term timescale with long-range temporal correlation (LRTC). It is unclear how the brain dynamics change in adult moyamoya disease (MMD). We used BOLD-fMRI for LRTC analysis from 16 hemorrhagic (H _MMD) and 34 ischemic (I _MMD) patients and 25 healthy controls. Afterwards, they were examined by EEG recordings in the eyes-closed (EC), eyes-open (EO), and working memory (WM) states. The EEG data of 11 H _MMD and 13 I _MMD patients and 21 healthy controls were in good quality for analysis. Regarding the 4 metrics of neural avalanches (e.g., size (α), duration (β)

SUBMITTER: Lei Y 

PROVIDER: S-EPMC8064775 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature