The Game of Tubulins.
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ABSTRACT:
SUBMITTER: Kristensson MA
PROVIDER: S-EPMC8065753 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Publications
Members of the tubulin superfamily are GTPases; the activities of GTPases are necessary for life. The members of the tubulin superfamily are the constituents of the microtubules and the γ-tubulin meshwork. Mutations in members of the tubulin superfamily are involved in developmental brain disorders, and tubulin activities are the target for various chemotherapies. The intricate functions (game) of tubulins depend on the activities of the GTP-binding domain of α-, β-, and γ-tubulin. This review c ...[more]
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