Unknown

Dataset Information

0

The Implementation of Mass-Vaccination against SARS-CoV-2: A Systematic Review of Existing Strategies and Guidelines.


ABSTRACT: The global drive to vaccinate against severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) began in December 2020 with countries in Europe, Middle East, and North America leading the roll out of a mass-vaccination program. This systematic review synthesised all available English-language guidelines and research regarding mass-vaccination for COVID-19 until 1 March 2021-the first three months of the global mass-vaccination effort. Data were extracted from national websites, PubMed, Embase, Medline and medRxiv, including peer and non-peer review research findings. A total of 15 national policy documents were included. Policies were summarised according to the World Health Organisation (WHO) framework for mass vaccination. All included policies prioritised front-line health care workers and the elderly. Limited information was available regarding staffing, cold chain, communication strategies and infrastructure requirements for effective vaccine delivery. A total of 26 research studies were identified, reporting roll-out strategies, vaccine uptake and reasons for refusal, adverse effects, and real-life estimates of efficacy. Early data showed a reduction in SARS-CoV-2 cases, hospitalisation and deaths in settings with good coverage. Very low rates of vaccine-related serious adverse events were observed. These findings provide an overview of current practice and early outcomes of COVID-19 mass-vaccination, guiding countries where roll-out is yet to commence.

SUBMITTER: Hasan T 

PROVIDER: S-EPMC8066252 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC9897643 | biostudies-literature
| S-EPMC8527734 | biostudies-literature
| S-EPMC7289747 | biostudies-literature
| S-EPMC8960152 | biostudies-literature
| S-EPMC8969402 | biostudies-literature
| S-EPMC8475973 | biostudies-literature
| S-EPMC9575573 | biostudies-literature
| S-EPMC9259875 | biostudies-literature
| S-EPMC8483984 | biostudies-literature
| S-EPMC8642950 | biostudies-literature