Validation of the Framingham hypertension risk score in a middle eastern population: Tehran lipid and glucose study (TLGS).

ABSTRACT:

Background

The Framingham hypertension risk score is a well-known and simple model for predicting hypertension in adults. In the current study, we aimed to assess the predictive ability of this model in a Middle Eastern population.

Methods

We studied 5423 participants, aged 20-69 years, without hypertension, who participated in two consecutive examination cycles of the Tehran Lipid and Glucose Study (TLGS). We assessed discrimination based on Harrell's concordance statistic (c-index) and calibration (graphical comparison of predicted vs. observed). We evaluated the original, recalibrated (for intercept and slope), and revised (for beta coefficients) models.

Results

Over the 3-year follow-up period, 319 participants developed hypertension. The Framingham hypertension r

SUBMITTER: Koohi F 

PROVIDER: S-EPMC8070324 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature