Project description:Primary cardiac tumors are rare, with an incidence of <0.1% in postmortem series; sarcomas comprise 75% of these. Cardiac sarcomas may be life-threatening at the time of presentation. We describe a left atrial intimal sarcoma presenting with constitutional symptoms, obstructive shock, and systemic emboli, and treated with proton beam therapy. (Level of Difficulty: Intermediate.).

| S-EPMC8311188 | biostudies-literature

An Extremely Rare Cause of Mitral Regurgitation-Accessory Commissural Mitral Tissue with Anomalous Left Atrial Chordal Attachment.

Project description: Not available

| S-EPMC6833125 | biostudies-literature

Left atrial myxoma causing near‐total mitral valve obstruction

Project description:Abstract Cardiac myxomas are the most common primary cardiac tumors in adults, with the left atrium being the most frequently affected. Echocardiography is the diagnostic modality of choice. The most effective treatment for cardiac myxomas is surgical excision. We present a clinical video of a large left atrial myxoma causing mitral valve obstruction, highlighting the importance of echocardiography as a diagnostic modality to facilitate referral to a tertiary center.

| S-EPMC9860133 | biostudies-literature

Primary cardiac intimal sarcoma masquerading as mitral stenosis.

Project description:Intimal sarcomas are a very rare medical entity and usually arise from the pulmonary artery or the thoracic aorta. Sarcomas should be considered in the differential diagnosis in patients with suspected mitral valve disease. Echocardiography should be performed as early as possible to establish a prompt diagnosis and management.

| S-EPMC5538049 | biostudies-other

A rare case of left atrial undifferentiated pleomorphic sarcoma.

Project description: Not available

| S-EPMC10572086 | biostudies-literature

Left atrial undifferentiated pleomorphic sarcoma causing left ventricular inflow tract obstruction: a case report

Project description: Not available

| S-EPMC10667031 | biostudies-literature

A case report of primary cardiac intimal sarcoma presenting with atrial fibrillation and a left atrial mass.

Project description:BackgroundIntimal sarcoma is an exceedingly rare type of primary cardiac tumour. It is characterized by poorly differentiated spindle-shaped cells that can mimic smooth muscle and is strongly associated with MDM2 genetic amplification. Owing to its rarity and non-distinctive histological features, diagnosis remains a significant challenge.Case summaryIn this case report, we describe a case of primary cardiac intimal sarcoma in a 37-year-old woman who presented with atrial fibrillation (AF) and a left atrial mass. Despite having a histological sample from an excised left atrial mass, the diagnosis was not made until she presented with back pain secondary to metastatic disease to the spine.DiscussionPrimary cardiac intimal sarcoma is an extremely rare diagnosis. The mainstay management of intimal cardiac sarcoma is aggressive surgical resection. Unfortunately, the prognosis of cardiac sarcomas remains very poor, with a mean survival between 3 months and 1 year. This case of cardiac intimal sarcoma highlights the difficulty in establishing a diagnosis, particularly given the unusual presentation of AF.

| S-EPMC8633751 | biostudies-literature

The elusive cause of syncope: Left atrial myxoma with mitral valve obstruction.

Project description:Key clinical messageSyncopal patients should be evaluated for cardiac causes, including myxoma, as highlighted in this case. Transthoracic echocardiography and coronary angiography are valuable diagnostic tools. Interventional cardiology plays a crucial role in the successful treatment of myxoma.AbstractThis case video describes the presentation and successful treatment of a 58-year-old woman who experienced recurrent episodes of syncope. After ruling out other health concerns, a pulmonary embolism was suspected and further investigations revealed a mass in the left atrium causing significant obstruction of the mitral valve. The mass, identified as a neovascularized myxoma, was successfully resected, emphasizing the significance of considering myxoma as a potential cause of syncope and highlighting the role of interventional cardiology in its management.

| S-EPMC10352547 | biostudies-literature

Anomalous left atrial chord as a rare cause of mitral regurgitation.

Project description: Not available

| S-EPMC7793040 | biostudies-literature