The Long-Term Effects of High-Fat and High-Protein Diets on the Metabolic and Endocrine Activity of Adipocytes in Rats.

ABSTRACT: The increasing prevalence of overweight and obesity and the rising awareness of their negative consequences are forcing researchers to take a new view of nutrition and its consequences for the metabolism of whole organisms as well as the metabolism of their individual systems and cells. Despite studies on nutrition having been carried out for a few decades, not many of them have focused on the impacts of these diets on changes in the metabolism and endocrine functions of isolated adipocytes. Therefore, we decided to investigate the effects of the long-term use (60 and 120 days) of a high-fat diet (HFD) and of a high-protein diet (HPD) on basic metabolic processes in fat cells-lipogenesis, lipolysis, and glucose uptake-and endocrine function, which was determined according to the secretion

SUBMITTER: Pruszynska-Oszmalek E 

PROVIDER: S-EPMC8073757 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature