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Effectiveness and resource requirements of test, trace and isolate strategies for COVID in the UK.


ABSTRACT: We use an individual-level transmission and contact simulation model to explore the effectiveness and resource requirements of various test-trace-isolate (TTI) strategies for reducing the spread of SARS-CoV-2 in the UK, in the context of different scenarios with varying levels of stringency of non-pharmaceutical interventions. Based on modelling results, we show that self-isolation of symptomatic individuals and quarantine of their household contacts has a substantial impact on the number of new infections generated by each primary case. We further show that adding contact tracing of non-household contacts of confirmed cases to this broader package of interventions reduces the number of new infections otherwise generated by 5-15%. We also explore impact of key factors, such as tracing application adoption and testing delay, on overall effectiveness of TTI.

SUBMITTER: He B 

PROVIDER: S-EPMC8074942 | biostudies-literature |

REPOSITORIES: biostudies-literature

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