Carbohydrate based meningococcal vaccines: past and present overview.
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ABSTRACT:
SUBMITTER: Berti F
PROVIDER: S-EPMC8076658 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Publications
Carbohydrate based meningococcal vaccines: past and present overview.
Berti Francesco F Romano Maria Rosaria MR Micoli Francesca F Adamo Roberto R
Glycoconjugate journal 20210427 4
Neisseria meningitidis is a major cause of bacterial meningitidis worldwide. Children less than five years and adolescents are particularly affected. Nearly all invasive strains are surrounded by a polysaccharide capsule, based on which, 12 N. meningitidis serogroups are differentiated. Six of them, A, B, C, W, X, and Y, cause the vast majority of infections in humans. Mono- and multi-valent carbohydrate-based vaccines against meningococcal infections have been licensed or are currently in clini ...[more]
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