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Predicting outcomes in older ED patients with influenza in real time using a big data-driven and machine learning approach to the hospital information system.


ABSTRACT:

Background

Predicting outcomes in older patients with influenza in the emergency department (ED) by machine learning (ML) has never been implemented. Therefore, we conducted this study to clarify the clinical utility of implementing ML.

Methods

We recruited 5508 older ED patients (≥65 years old) in three hospitals between 2009 and 2018. Patients were randomized into a 70%/30% split for model training and testing. Using 10 clinical variables from their electronic health records, a prediction model using the synthetic minority oversampling technique preprocessing algorithm was constructed to predict five outcomes.

Results

The best areas under the curves of predicting outcomes were: random forest model for hospitalization (0.840), pneumonia (0.765), and sepsis or septic shock (0.857), XGBoost for intensive care unit admission (0.902), and logistic regression for in-hospital mortality (0.889) in the testing data. The predictive model was further applied in the hospital information system to assist physicians' decisions in real time.

Conclusions

ML is a promising way to assist physicians in predicting outcomes in older ED patients with influenza in real time. Evaluations of the effectiveness and impact are needed in the future.

SUBMITTER: Tan TH 

PROVIDER: S-EPMC8077903 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Publications

Predicting outcomes in older ED patients with influenza in real time using a big data-driven and machine learning approach to the hospital information system.

Tan Tian-Hoe TH   Hsu Chien-Chin CC   Chen Chia-Jung CJ   Hsu Shu-Lien SL   Liu Tzu-Lan TL   Lin Hung-Jung HJ   Wang Jhi-Joung JJ   Liu Chung-Feng CF   Huang Chien-Cheng CC  

BMC geriatrics 20210427 1


<h4>Background</h4>Predicting outcomes in older patients with influenza in the emergency department (ED) by machine learning (ML) has never been implemented. Therefore, we conducted this study to clarify the clinical utility of implementing ML.<h4>Methods</h4>We recruited 5508 older ED patients (≥65 years old) in three hospitals between 2009 and 2018. Patients were randomized into a 70%/30% split for model training and testing. Using 10 clinical variables from their electronic health records, a  ...[more]

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