Ontology highlight
ABSTRACT:
SUBMITTER: Palmer J
PROVIDER: S-EPMC8078675 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Palmer Joanne J Pymer Sean S Smith George E GE Harwood Amy Elizabeth AE Ingle Lee L Huang Chao C Chetter Ian C IC
The Cochrane database of systematic reviews 20200921
<h4>Background</h4>Lower limb peripheral arterial disease (PAD) is a type of cardiovascular disease where the blood vessels that carry the blood to the legs are hardened and narrowed. The most severe manifestation of PAD is critical limb ischaemia (CLI). This condition results in symptoms of intractable rest pain, non-healing wounds and ulceration, gangrene or both. PAD affects more than 200 million people worldwide and approximately 3% to 5% of people aged over 40 have PAD, rising to 18% in peo ...[more]