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Successful medical management of fungal infective endocarditis post VSD closure.

ABSTRACT: Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3'-6.8' of all IE cases and is considered the most severe form with a mortality rate as high as 45'-50'. There are various predisposing factors for fungal IE which include congenital heart defects, cardiac interventions like pacemaker insertion, degenerative valvular heart diseases, long-term use of broad-spectrum antimicrobial therapy, and long-term use of central venous. Mortality can reach up to 100' without specific treatment. Definitive therapy necessitates surgical debridement of vegetations/mass/abscess followed by long-term treatment with antifungal agents in patients who have symptoms of heart failure despite optimum medical management. We, hereby, report a case of fungal IE which occurred after the closure of a ventricular septal defect and was treated successfully with liposomal amphotericin B.

SUBMITTER: Prasad Gourav KK

PROVIDER: S-EPMC8081123 | biostudies-literature | 2021 Jan-Mar

REPOSITORIES: biostudies-literature

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Successful medical management of fungal infective endocarditis post VSD closure.

Prasad Gourav Kalla Krishna KK Mandal Banashree B Mishra Anand Kumar AK Narayanan Nayanar V Krishna VK

Annals of cardiac anaesthesia 20210101 1

Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3'-6.8' of all IE cases and is considered the most severe form with a mortality rate as high as 45'-50'. There are various predisposing factors for fungal IE which include congenital heart defects, cardiac interventions like pacemaker insertion, degenerative valvular heart diseases, long-term use of broad-spectrum antimicrobial therapy, and long-term use of central venous. Mort ...[more]

PMID: 33938843

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