Trajectories of cognitive function in community-dwelling older adults: A longitudinal study of population heterogeneity.

ABSTRACT:

Introduction

This study aimed to investigate cognitive aging trajectories, the associated sociodemographic characteristics, and the association of these trajectories with dementia.

Methods

Generally healthy older adults (n = 19,114) were followed for up to 7 years, with regular cognitive assessments. Group-based trajectory modeling identified distinct cognitive trajectories.

Results

Four to seven trajectories were identified per cognitive domain. Stable trajectories were observed across domains. Improvement in verbal fluency and minor psychomotor slowing were common. Substantial decline in global cognition and episodic memory were observed in a small proportion of individuals. Older, less educated participants and men were more common in lower-functioning trajectories

SUBMITTER: Wu Z 

PROVIDER: S-EPMC8088593 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature