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Quantifying interfacial substrate interactions via surface energy analyses.

ABSTRACT: Determination of a substrate's surface energy profile is a facile and inexpensive method to indicate the substrate's interfacial thermodynamics with another substance (e.g., microorganisms, biomacromolecules, medical devices, etc). The following protocol details a goniometric method to calculate a substrate's surface energy profile which (1) directly correlates to a substrate's interfacial Gibbs energy (ΔG) and (2) predicts the interfacial interactions with other substances. We also provide a calculation template using advanced mathematics to expedite surface energy profile determination. For complete details on the use and execution of this protocol, please refer to Cavitt et al. (2020).

SUBMITTER: Cavitt TB

PROVIDER: S-EPMC8091927 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Quantifying interfacial substrate interactions via surface energy analyses.

Cavitt T Brian TB Carlisle Jasmine G JG Brooks Rachel A RA Scott Lauren G LG Patel Pooja R PR

STAR protocols 20210421 2

Determination of a substrate's surface energy profile is a facile and inexpensive method to indicate the substrate's interfacial thermodynamics with another substance (e.g., microorganisms, biomacromolecules, medical devices, etc). The following protocol details a goniometric method to calculate a substrate's surface energy profile which (1) directly correlates to a substrate's interfacial Gibbs energy (ΔG) and (2) predicts the interfacial interactions with other substances. We also provide a ca ...[more]

PMID: 33997808

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