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BKC-2, a New BKC Variant Detected in MCR-9.1-Producing Enterobacter hormaechei subsp. xiangfangensis.


ABSTRACT: We characterized a multidrug-resistant (MDR) Enterobacter spp. isolate highlighting the genetic aspects of the antimicrobial resistance genes. An Enterobacter spp. isolate (Ec61) was recovered in 2014 from a transtracheal aspirate sample from a patient admitted to a Brazilian tertiary hospital and submitted to further microbiological and genomic characterization. Ec61 was identified as Enterobacter hormaechei subsp. xiangfangensis strain ST451, showing an MDR profile and the presence of genes codifying the new β-lactamase variants BKC-2 and ACT-84 and the mobile colistin resistance gene mcr-9.1.

SUBMITTER: Martins WMBS 

PROVIDER: S-EPMC8092528 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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BKC-2, a New BKC Variant Detected in MCR-9.1-Producing Enterobacter hormaechei subsp. <i>xiangfangensis</i>.

Martins Willames M B S WMBS   Martins Evelin R ER   de Andrade Letícia K LK   Farzana Refath R   Walsh Timothy R TR   Toleman Mark A MA   Nogueira Mara C L MCL   Gales Ana C AC  

Antimicrobial agents and chemotherapy 20210217 3


We characterized a multidrug-resistant (MDR) <i>Enterobacter</i> spp. isolate highlighting the genetic aspects of the antimicrobial resistance genes. An <i>Enterobacter</i> spp. isolate (Ec61) was recovered in 2014 from a transtracheal aspirate sample from a patient admitted to a Brazilian tertiary hospital and submitted to further microbiological and genomic characterization. Ec61 was identified as <i>Enterobacter hormaechei</i> subsp. <i>xiangfangensis</i> strain ST451, showing an MDR profile  ...[more]

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