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Platinum-containing regimens for triple-negative metastatic breast cancer.


ABSTRACT:

SUBMITTER: Egger SJ 

PROVIDER: S-EPMC8092567 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Platinum-containing regimens for triple-negative metastatic breast cancer.

Egger Sam J SJ   Chan Matthew Ming Ki MMK   Luo Qingwei Q   Wilcken Nicholas N  

The Cochrane database of systematic reviews 20201021


<h4>Background</h4>In a previous Cochrane Review, we found that for women with metastatic breast cancer unselected for triple-negative disease, there is little or no survival benefit and excess toxicity from platinum-based regimens. In subgroup analyses, however, we found preliminary low-quality evidence of a survival benefit from platinum-based regimens for women with metastatic triple-negative breast cancer (mTNBC). This review updates the evidence from the mTNBC subgroup analyses in the previ  ...[more]

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