Ontology highlight
ABSTRACT:
SUBMITTER: Scheiman M
PROVIDER: S-EPMC8092638 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Alkan Şen Gülin G Şentürk Öztaş Nihan N Değerli Ezgi E Can Günay G Turna Hande H Özgüroğlu Mustafa M
Lung cancer (Amsterdam, Netherlands) 20230816
<h4>Background</h4>Gut microbiotaplays a crucial role in immune response. Recent data have shown that antibiotic (ATB) usage influences efficacy of immune check point inhibitors (ICIs) via altering microbiota of the gut.<h4>Methods</h4>We retrospectively analyzed patients with advanced non-small cell lung cancer (NSCLC) treated with ICIs as monotherapy or combination with chemotherapy (ChT) at the one academic center. Those receiving ATB for the first 12 weeks of the initiation of ICIs were comp ...[more]