Clinical and CT characteristics of Xpert MTB/RIF-negative pulmonary tuberculosis.

ABSTRACT:

Purpose

To determine the diagnostic accuracy of the Xpert MTB/RIF assay in patients with smear-negative pulmonary tuberculosis (TB) and to assess clinical and CT characteristics of Xpert-negative pulmonary TB.

Material and methods

We retrospectively reviewed the records of 1,400 patients with suspected pulmonary TB for whom the sputum Xpert MTB/RIF assay was performed between September 1, 2014 and February 28, 2020. Clinical and CT characteristics of smear-negative pulmonary TB patients with negative Xpert MTB/RIF results were compared with positive results.

Results

Of 1,400 patients, 365 (26.1%) were diagnosed with pulmonary TB and 190 of 365 patients (52.1%) were negative for sputum acid-fast bacilli. The diagnosis of pulmonary TB was based on a positive culture, po

SUBMITTER: Lee HN 

PROVIDER: S-EPMC8092799 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature