Ontology highlight
ABSTRACT:
SUBMITTER: Yi JH
PROVIDER: S-EPMC8093997 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Blood research 20210401 S1
Despite substantially improved survival with rituximab-based treatment regimens, there is an unmet medical need for better treatments of B-cell lymphoma, particularly for patients with relapsed or refractory disease. Retreatment with rituximab exerts a limited effect in these patients, and platinum-based salvage treatment followed by autologous stem cell transplantation remains the only curative option. Recent strategies have focused on targeting novel B-cell surface markers, inhibiting B-cell r ...[more]