TRTools: a toolkit for genome-wide analysis of tandem repeats.
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ABSTRACT: Summary
A rich set of tools have recently been developed for performing genome-wide genotyping of tandem repeats (TRs). However, standardized tools for downstream analysis of these results are lacking. To facilitate TR analysis applications, we present TRTools, a Python library and suite of command line tools for filtering, merging and quality control of TR genotype files. TRTools utilizes an internal harmonization module, making it compatible with outputs from a wide range of TR genotypers.Availability and implementation
TRTools is freely available at https://github.com/gymreklab/TRTools. Detailed documentation is available at https://trtools.readthedocs.io.Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Mousavi N
PROVIDER: S-EPMC8097685 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Publications
TRTools: a toolkit for genome-wide analysis of tandem repeats.
Mousavi Nima N Margoliash Jonathan J Pusarla Neha N Saini Shubham S Yanicky Richard R Gymrek Melissa M
Bioinformatics (Oxford, England) 20210501 5
<h4>Summary</h4>A rich set of tools have recently been developed for performing genome-wide genotyping of tandem repeats (TRs). However, standardized tools for downstream analysis of these results are lacking. To facilitate TR analysis applications, we present TRTools, a Python library and suite of command line tools for filtering, merging and quality control of TR genotype files. TRTools utilizes an internal harmonization module, making it compatible with outputs from a wide range of TR genotyp ...[more]
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