Ontology highlight
ABSTRACT:
SUBMITTER: Youn YJ
PROVIDER: S-EPMC8099611 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Youn Young-Jin YJ Lee Yu-Bin YB Kim Sun-Hwa SH Jin Hee Kyung HK Bae Jae-Sung JS Hong Chang-Won CW
Immune network 20210223 2
Patients with severe coronavirus disease 2019 (COVID-19) demonstrate dysregulated immune responses including exacerbated neutrophil functions. Massive neutrophil infiltrations accompanying neutrophil extracellular trap (NET) formations are also observed in patients with severe COVID-19. However, the mechanism underlying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced NET formation has not yet been elucidated. Here we show that 2 viral proteins encoded by SARS-CoV-2, the nucl ...[more]