Ontology highlight
ABSTRACT:
SUBMITTER: Bian G
PROVIDER: S-EPMC8104937 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Bian Guohui G Gu Yanzheng Y Xu Changlu C Xu Changlu C Yang Wenyu W Pan Xu X Chen Yijin Y Lai Mowen M Zhou Ya Y Dong Yong Y Mao Bin B Zhou Qiongxiu Q Chen Bo B Nakathata Tatsutoshi T Shi Lihong L Wu Min M Zhang Yonggang Y Ma Feng F
Journal of molecular cell biology 20210501 2
Mast cells (MCs) play a pivotal role in the hypersensitivity reaction by regulating the innate and adaptive immune responses. Humans have two types of MCs. The first type, termed MCTC, is found in the skin and other connective tissues and expresses both tryptase and chymase, while the second, termed MCT, which only expresses tryptase, is found primarily in the mucosa. MCs induced from human adult-type CD34+ cells are reported to be of the MCT type, but the development of MCs during embryonic/fet ...[more]