Role of a successful spontaneous breathing trial in ventilator liberation in brain-injured patients.

ABSTRACT:

Background

Spontaneous breathing trials (SBTs) have been shown to improve outcomes in critically ill patients. However, in patients with brain injury, indications for intubation and mechanical ventilation are different from those of non-neurological patients, and the role of an SBT in patients with brain injury is less established. The aim of the present study was to compare key respiratory variables acquired during a successful SBT between patients with successful ventilator liberation versus failed ventilator liberation.

Methods

In this prospective study, patients with brain injury (≥18 years of age), who completed a 30-min SBT, were enrolled. Airway pressure, flow, esophageal pressure, and diaphragm electrical activity (ΔEAdi) were recorded before (baseline) and during th

SUBMITTER: Shi ZH 

PROVIDER: S-EPMC8105847 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature