Dataset Information

Prevalence of postamputation pain and its subtypes: a meta-analysis with meta-regression.

ABSTRACT:

Introduction

The inconsistent use of standardized approaches for classifying postamputation pain (PAP) has been a barrier to establishing its prevalence.

Objectives

The primary objective of this systematic review and meta-analysis is to determine the prevalence of nontraumatic lower-extremity PAP using an established taxonomy. The secondary objective is to determine the prevalence of PAP subtypes, including phantom limb pain and residual limb pain (RLP).

Methods

An a priori protocol was registered, and a database search was conducted by a reference librarian. Randomized trials and uncontrolled studies were eligible for inclusion. The risk of bias was assessed using a tool developed for uncontrolled studies. A total of 2679 studies were screened, and 13 studies met inclusion criteria (n = 1063).

Results

The sources of risk of bias included selection bias and, to a lesser extent, whether the outcome was adequately ascertained. Two studies reported the prevalence of PAP and the pooled prevalence was 61% (95% confidence interval [CI], 33%-86%) with high heterogeneity (I² = 93%). Thirteen studies reported the prevalence of phantom limb pain and the pooled prevalence was 53% (95% CI, 40%-66%) with high heterogeneity (I² = 93%). Eight studies reported the prevalence of RLP and the pooled prevalence was 32% (95% CI 24%-41%) with high heterogeneity (I² = 76%). Clinical subtypes of RLP were not reported.

Conclusions

The prevalence of PAP is high in patients with nontraumatic lower-extremity amputations. Ongoing research that uses a taxonomy for PAP is needed to fully delineate the prevalence of PAP subtypes.

SUBMITTER: Schwingler PM

PROVIDER: S-EPMC8108594 | biostudies-literature | 2021 Jan-Feb

REPOSITORIES: biostudies-literature

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Publications

Prevalence of postamputation pain and its subtypes: a meta-analysis with meta-regression.

Schwingler Paul M PM Moman Rajat N RN Hunt Christy C Ashmore Zachary Z Ogletree Sandra P SP Uvodich Mason E ME Murad M Hassan MH Hooten W Michael WM

Pain reports 20210101 1

<h4>Introduction</h4>The inconsistent use of standardized approaches for classifying postamputation pain (PAP) has been a barrier to establishing its prevalence.<h4>Objectives</h4>The primary objective of this systematic review and meta-analysis is to determine the prevalence of nontraumatic lower-extremity PAP using an established taxonomy. The secondary objective is to determine the prevalence of PAP subtypes, including phantom limb pain and residual limb pain (RLP).<h4>Methods</h4>An a priori ...[more]

PMID: 33981935

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Dataset Information

Prevalence of postamputation pain and its subtypes: a meta-analysis with meta-regression.

Introduction

Objectives

Methods

Results

Conclusions

Publications

Prevalence of postamputation pain and its subtypes: a meta-analysis with meta-regression.

Similar Datasets

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