Perfluoroalkyl acids, hyperuricemia and gout in adults: Analyses of NHANES 2009-2014.

ABSTRACT:

Background

Previous studies have reported a positive association of perfluoralkyl acids (PFAAs), including perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS), with hyperuricemia. The objective of the study is to investigate whether there is an association between concurrent serum levels of several PFAAs and gout, serum uric acid (SUA) or hyperuricemia in the U.S. adult population as represented by the National Health and Nutrition Examination Survey (NHANES) 2009-2014 sample (n = 4917). The PFAAs investigated include PFOA, perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluorohexane sulfonic acid (PFHxS) and PFOS.

Methods

This cross-sectional study used multivariate logistic regressions to analyze the association of single PFAAs with hyperuri

SUBMITTER: Scinicariello F 

PROVIDER: S-EPMC8114790 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature