Outcomes of Hypertensive Kidney Donors Using Current and Past Hypertension Definitions.

ABSTRACT:

Introduction

As many as 50% of U.S. transplant centers do not accept kidney donor candidates with hypertension, citing the link between hypertension, kidney disease, and cardiovascular disease (CVD).

Methods

We ascertained mortality, CVD, proteinuria, estimated glomerular filtration rate (eGFR) trajectory, reduced eGFR, and end-stage kidney disease (ESKD) in 904 hypertensive donors (blood pressure [BP] ≥140/90 mm Hg or receiving treatment) versus 7817 donors with BP <140/90 mm Hg.

Results

Hypertensive donors were older, 58.1% were <50 years of age, and they had a lower eGFR. The majority were white and related to their recipient. At the end of follow-up, 14.3 ± 10.1 years (range 4-48 years) from donation, hypertensive and nonhypertensive donors had a similar prevalenc

SUBMITTER: Ibrahim HN 

PROVIDER: S-EPMC8116910 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature