Temporal trends in risk profiles among patients hospitalized for heart failure.

ABSTRACT:

Background

Postdischarge mortality following hospitalization for heart failure with reduced ejection fraction (HFrEF) has remained high and unchanged over the past 2 decades, despite effective therapies for HFrEF. We aimed to explore whether these patterns could in part be explained by changes in longitudinal risk profile and HF severity over time.

Methods

Among patients hospitalized for HF in the GWTG-HF registry from January 2005 to December 2018 with available data, we evaluated GWTG-HF and ADHERE risk scores, observing in-hospital mortality per-year. The risk profiles and outcomes were described overall and by subgroups based on ejection fraction (EF), diabetes mellitus (DM), sex, and age.

Results

Overall, 335,735 patients were included (50% HFrEF, 46% DM, 48% fem

SUBMITTER: Hamo CE 

PROVIDER: S-EPMC8120737 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature