Antidepressant and anticonvulsant prescription rates in patients with osteoarthritis: a population-based cohort study.

ABSTRACT:

Objectives

There are signs that antidepressants and anticonvulsants are being prescribed more often for OA patients, despite limited evidence. Our objectives were to examine prescription rates and time trends for antidepressants and anticonvulsants in OA patients, to assess the percentage of long-term prescriptions, and to determine patient characteristics associated with antidepressant or anticonvulsant prescription.

Methods

A population-based cohort study was conducted using the Integrated Primary Care Information database. First, episodic and prevalent prescription rates for antidepressants (amitriptyline, nortriptyline and duloxetine) and anticonvulsants (gabapentinoids) in OA patients were calculated for the period 2008-17. Logistic regression was used to assess which p

SUBMITTER: van den Driest JJ 

PROVIDER: S-EPMC8121444 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature