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Cell-level metadata are indispensable for documenting single-cell sequencing datasets.


ABSTRACT: Single-cell RNA sequencing (scRNA-seq) provides an unprecedented view of cellular diversity of biological systems. However, across the thousands of publications and datasets generated using this technology, we estimate that only a minority (<25%) of studies provide cell-level metadata information containing identified cell types and related findings of the published dataset. Metadata omission hinders reproduction, exploration, validation, and knowledge transfer and is a common problem across journals, data repositories, and publication dates. We encourage investigators, reviewers, journals, and data repositories to improve their standards and ensure proper documentation of these valuable datasets.

SUBMITTER: Puntambekar S 

PROVIDER: S-EPMC8121533 | biostudies-literature |

REPOSITORIES: biostudies-literature

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