Supramolecular associations between atypical oxidative phosphorylation complexes of Euglena gracilis.

ABSTRACT: In vivo associations of respiratory complexes forming higher supramolecular structures are generally accepted nowadays. Supercomplexes (SC) built by complexes I, III and IV and the so-called respirasome (I/III₂/IV) have been described in mitochondria from several model organisms (yeasts, mammals and green plants), but information is scarce in other lineages. Here we studied the supramolecular associations between the complexes I, III, IV and V from the secondary photosynthetic flagellate Euglena gracilis with an approach that involves the extraction with several mild detergents followed by native electrophoresis. Despite the presence of atypical subunit composition and additional structural domains described in Euglena complexes I, IV and V, canonical associations into III₂

SUBMITTER: Miranda-Astudillo HV 

PROVIDER: S-EPMC8124061 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature