Ontology highlight
ABSTRACT:
SUBMITTER: Park KS
PROVIDER: S-EPMC8125125 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Park Kyung-Sun KS Lee Woochang W Seong Moon-Woo MW Kong Sun-Young SY Lee Kyung-A KA Ha Jung-Sook JS Cho Eun-Hae EH Han Sung-Hee SH Park Inho I Kim Jong-Won JW
Cancers 20210502 9
In this study, we performed a comprehensive analysis of <i>BRCA1</i>/<i>2</i> variants and associated cancer risk in Korean patients considering two aspects: variants of uncertain significance (VUS) and pathogenic or likely pathogenic variants (PLPVs) in <i>BRCA1</i> and <i>BRCA2</i>. This study included 5433 Korean participants who were tested for <i>BRCA1/2</i> genes. The <i>BRCA1/2</i> variants were classified following the standards/guidelines for interpretation of genetic variants and using ...[more]