Evaluating anemia using contrast-enhanced spectral detector CT of the chest in a large cohort of 522 patients.

ABSTRACT:

Objectives

The blood of patients with anemia demonstrates distinctly lower attenuation in unenhanced CT images. However, the frequent usage of intravenous contrast hampers evaluation of anemia. Spectral detector computed tomography (SDCT) allows for reconstruction of virtual non-contrast images (VNC) from contrast-enhanced data (CE). The purpose of this study was to evaluate whether VNC allow for prediction of anemia.

Methods

Five hundred twenty-two patients with CE-SDCT of the chest and accessible serum hemoglobin (HbS) were retrospectively included. Patients were assigned to three groups (severe anemia, moderate/mild anemia, and healthy) based on recent lab tests (≤ 7 days) for HbS following gender and the WHO definition of anemia. CT attenuation was determined using two R

SUBMITTER: Zopfs D 

PROVIDER: S-EPMC8128794 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature