Relation between preoperative benzodiazepines and opioids on outcomes after total joint arthroplasty.

ABSTRACT: To examine the association of preoperative opioids and/or benzodiazepines on postoperative outcomes in total knee and hip arthroplasty, we retrospectively compared postoperative outcomes in those prescribed preoperative opioids and/or benzodiazepines versus those who were not who underwent elective total knee and hip arthroplasty at a single urban academic institution. Multivariable logistic regression was performed for readmission rate, respiratory failure, infection, and adverse cardiac events. Multivariable zero-truncated negative binomial regression was used for length of stay. After exclusions, there were 4307 adult patients in the study population, 2009 of whom underwent total knee arthroplasty and 2298 of whom underwent total hip arthroplasty. After adjusting for potential confounde

SUBMITTER: Doan LV 

PROVIDER: S-EPMC8131602 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature