Antibody Response to COVID-19 vaccination in Patients Receiving Dialysis.

ABSTRACT: Patients receiving dialysis may mount impaired responses to COVID19 vaccination. We report antibody response to vaccination from 1140 patients without, and 493 patients with pre-vaccination SARS-CoV-2 RBD antibody. We used commercially available assays (Siemens) to test remainder plasma monthly in association with vaccination date and type, and assess prevalence of absent total receptor binding antibody, and absent or attenuated (index value < 10) semiquantitative receptor binding domain IgG index values. We used Poisson regression to evaluate risk factors for absent or attenuated response to vaccination. Among patients who were seronegative versus seropositive before vaccination, 62% and 56% were ≥65 years old, 20% and 24% were Hispanic, and 22% and 23% were Black. Median IgG index values

SUBMITTER: Anand S 

PROVIDER: S-EPMC8132255 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature