Unknown

Dataset Information

0

A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal.

ABSTRACT: Two siblings with the same male unbalanced karyotype demonstrate sex reversal. The older sib appeared phenotypically female and the younger sib demonstrated a male gender. The female had gonadal dysgenesis with bilateral ovatestes. The male had bilateral testes. The report discusses the phenotypical differences and genes associated with sex reversal.

SUBMITTER: Cordes Selby S 

PROVIDER: S-EPMC8136447 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal.

Cordes Selby Susan S   Iwata-Otsubo Aiko A   Delk Paula P   Nebesio Todd D TD   Gohil Anisha A   Matlock Peggy P   Torres-Martinez Wilfredo W   Vance Gail H GH  

Clinical case reports 20210506 5

Two siblings with the same male unbalanced karyotype demonstrate sex reversal. The older sib appeared phenotypically female and the younger sib demonstrated a male gender. The female had gonadal dysgenesis with bilateral ovatestes. The male had bilateral testes. The report discusses the phenotypical differences and genes associated with sex reversal. ...[more]

Similar Datasets

Unknown Having a brother or sister with Down syndrome: perspectives from siblings.
| S-EPMC3348944 | biostudies-literature
Unknown Programs to Prepare Siblings for Future Roles to Support Their Brother or Sister with a Neurodevelopmental Disability: a Scoping Review.
| S-EPMC9942034 | biostudies-literature
Unknown Programmes to prepare siblings for future roles to support their brother or sister with a neurodisability: protocol of a scoping review.
| S-EPMC8264900 | biostudies-literature
Unknown Big Sister, Big Brother: A Mixed Methods Study on Older Siblings’ Role in Infant and Young Child Feeding and Care in Rural Tanzania (P10-020-19)
| S-EPMC6574354 | biostudies-literature
Unknown Sister, Sister! Siblings With Simultaneous Early Femoral Insufficiency Fractures After Total Knee Arthroplasty.
| S-EPMC7856391 | biostudies-literature
Unknown From karyotypes to precision genomics in 9p deletion and duplication syndromes.
| S-EPMC8756500 | biostudies-literature
Unknown Xq21.1q21.31 Duplication in Two Male Siblings.
| S-EPMC8928204 | biostudies-literature
Unknown Case series: clinical outcomes of the transthyretin valine-to-isoleucine mutation in a brother-sister pair.
| S-EPMC6426053 | biostudies-literature
Unknown De Novo Duplication of Chromosome 9p in a Female Infant: Phenotype and Genotype Correlation.
| S-EPMC6976307 | biostudies-literature
Unknown Case report: Biallelic variants in POLR3B gene lead to 4H leukodystrophy from the study of brother and sister.
| S-EPMC9410618 | biostudies-literature