Ontology highlight
ABSTRACT:
SUBMITTER: Tran PLT
PROVIDER: S-EPMC8136832 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Tran Phong Lan Thao PLT Rieu Martin M Hodeib Samar S Joubert Alexandra A Ouellet Jimmy J Alberti Patrizia P Bugaut Anthony A Allemand Jean-François JF Boulé Jean-Baptiste JB Croquette Vincent V
Nucleic acids research 20210501 9
G-quadruplex (G4) DNA structures have emerged as important regulatory elements during DNA metabolic transactions. While many in vitro studies have focused on the kinetics of G4 formation within DNA single-strands, G4 are found in vivo in double-stranded DNA regions, where their formation is challenged by the complementary strand. Since the energy of hybridization of Watson-Crick structures dominates the energy of G4 folding, this competition should play a critical role on G4 persistence. To addr ...[more]