Effect of Helicobacter pylori treatment on the long-term mortality in patients with type 2 diabetes.

ABSTRACT:

Background/aims

Meta-analyses of randomized trials reported a non-significant increase in overall mortality risk after Helicobacter pylori eradication. In this study, we investigated whether H. pylori treatment is associated with increased risk of overall mortality in patients with type 2 diabetes.

Methods

In this retrospective population-based cohort study, we identified 66,706 patients treated for type 2 diabetes between 2002 and 2010 from the Korean National Health Insurance Service-National Sample Cohort. Patients who received H. pylori treatment (Hp-treatment cohort, 1,727 patients) were matched to those who did not (non-treatment cohort, 3,454 patients) at a 1:2 ratio. The primary outcome was overall mortality. The secondary outcomes were mortalities due to cardiovascu

SUBMITTER: Kim YI 

PROVIDER: S-EPMC8137405 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature