Evaluation of potency of the selected bioactive molecules from Indian medicinal plants with M^Pro of SARS-CoV-2 through in silico analysis.

ABSTRACT:

Background

The recent outbreak of the novel SARS-CoV-2 across the globe and the absence of specific drug against this virus lead the scientific community to look into some alternative indigenous treatments. India as a hub of Ayurvedic and medicinal plants can shed light on its treatment using specific active bio-molecules from these plants.

Objectives

Keeping our herbal resources in mind, we were interested to inquire whether some phytochemicals from Indian spices and medicinal plants can be used as alternative therapeutic agents in contrast to synthetic drugs.

Materials and methods

We used in silico molecular docking approach to test whether bioactive molecules of herbal origin such as hyperoside, nimbaflavone, ursolic acid, 6-gingerol, 6-shogaol and 6-

SUBMITTER: Halder P 

PROVIDER: S-EPMC8139275 | biostudies-literature | 2022 Apr-Jun

REPOSITORIES: biostudies-literature